Key result
Coronary sinus dilatation strongly correlates with severe rheumatic valve disease.
Why the study?
The usefulness of coronary sinus anatomic diameter as an additional surrogate marker of severity in chronic rheumatic valve disease was not established.
Does coronary sinus dilatation correlate with the severity of chronic rheumatic mitral and tricuspid valve disease?
Cross-Sectional (n=192)
No
Does coronary sinus dilatation correlate with the severity of chronic rheumatic mitral and tricuspid valve disease?
Echocardiographic assessment of coronary sinus dilatation may serve as a simple, additional surrogate marker for predicting the severity of rheumatic mitral and tricuspid valve disease.
May support coronary sinus dilatation as a severity marker in rheumatic disease; leaves open its incremental value without prospective validation.
OBJECTIVE: To evaluate the usefulness of examining the coronary sinus (CS) anatomic diameter as an additional surrogate marker of severity in chronic rheumatic valve disease (RVD). METHODS: In this cross-sectional observational study, we echocardiographically analyzed 88 patients with RVD, and 104 normal subjects in the Department of Cardiology, Gaziantep University Medical Faculty, Gaziantep, Turkey between February 2007 and April 2007. Echocardiographically all valve regurgitation, stenosis, left ventricular function, left/right atrial volume, and pulmonary artery pressure were obtained. Coronary sinus was assessed as a sonolucency in the posterior atrioventricular groove. RESULTS: Strong positive correlation was present between CS measurements and mitral mean gradient, mitral and tricuspid regurgitation grade, tricuspid stenosis gradient, pulmonary artery systolic pressure, left and right atrial volume, and New York Heart Association class. A statistically negative correlation was present between CS measurements and mitral valve area and ejection fraction. Only the mitral valve area, tricuspid regurgitation grade, and the right atrial volume were predictors of body surface area adjusted mean CS dilatation. CONCLUSION: In this preliminary study, we showed that echocardiographic assessment of dilated CS may provide useful additional information in predicting the severity of mitral/tricuspid RVD. Findings of this study needs to be confirmed in further studies.
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Kızılkan et al. (2010) conducted a cross-sectional in chronic rheumatic valve disease (RVD) (n=192). Coronary sinus dilatation vs. Normal subjects was evaluated on Correlation between coronary sinus measurements and echocardiographic parameters of valve disease severity. Coronary sinus dilatation strongly correlated with mitral mean gradient, regurgitation grades, and right atrial volume, serving as an indicator of severe rheumatic valve disease.
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