Why the study?
The study aimed to evaluate the prevalence of polypharmacy and potentially inappropriate medications and assess their association with cognitive impairment in institutionalized older adults.
Population
193 nursing home residents in Viseu, Portugal
Design
Cross-sectional study
Key result
Polypharmacy (80.8% prevalence) and potentially inappropriate medications (79.3% prevalence) were significantly associated with lower MMSE scores (p=0.039 and p<0.001) in nursing home residents.
Authors
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May support medication review in nursing homes; leaves open causal effects on cognition in prospective studies.
Cross-Sectional (n=193)
Yes
p-value: p=<0.001
High prevalence of polypharmacy and potentially inappropriate medications in institutionalized older adults is significantly associated with cognitive impairment.
Caçador et al. (2022) conducted a cross-sectional in Cognitive impairment in institutionalized older adults (n=193). Polypharmacy and potentially inappropriate medications vs. Lower medication intake was evaluated on Cognitive impairment (MMSE scores) (p=<0.001). Polypharmacy (80.8% prevalence) and potentially inappropriate medications (79.3% prevalence) were significantly associated with lower MMSE scores (p=0.039 and p<0.001) in nursing home residents.
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