February 28, 2016International Journal of Geriatric Psychiatry
Potentially inappropriate medications and drug–drug interactions in home‐dwelling people with mild dementia
Key result
Among home-dwelling patients with mild dementia, nearly 70% used psychotropic drugs, 45% had polypharmacy, and 14% had potentially inappropriate medications.
Population
251 home-dwelling patients with a first-time diagnosis of mild dementia from outpatient clinics
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
High psychotropic use in mild dementia outpatients warrants review; cross-sectional data leaves open effects on outcomes.
Study Design
Type
Cross-Sectional (n=251)
Multicenter
Yes
Structured PICO
P
Population
251 home-dwelling patients with a first-time diagnosis of mild dementia (MMSE >20) recruited from outpatient clinics.
O
Outcome
Prevalence of psychotropic drug use, polypharmacy, psychotropic polypharmacy, potentially inappropriate medications (PIM), and drug-drug interactions (DDI)safety
In home-dwelling patients with mild dementia, potentially inappropriate medications and severe drug-drug interactions are relatively uncommon, though psychotropic drug use is highly prevalent.
Cite This Study
Oesterhus et al. (2016) conducted a cross-sectional in mild dementia (n=251). Psychotropic drugs and potentially inappropriate medications was evaluated on Prevalence of psychotropic drug use, polypharmacy, potentially inappropriate medications (PIM), and drug-drug interactions (DDI). Among home-dwelling patients with mild dementia, nearly 70% used psychotropic drugs, 45% had polypharmacy, and 14% had potentially inappropriate medications.