Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 1, 2023BMJ Case ReportsOpen Access

Wernicke encephalopathy: limitations in a laboratory and radiological diagnosis

View Full Paper
Ask AI
Bookmark
Share

Authors

KOKohei OnoSHSatoshi HayanoMKMasayuki Kashima

Discussion

Loading...

Member takes

Overview

Case report demonstrates the need for timely treatment of Wernicke encephalopathy despite normal thiamine levels.

Key Points

  • This report aims to highlight the diagnostic challenges of Wernicke encephalopathy, particularly with normal thiamine levels.
  • Case presentation of a male patient in his 70s with a history of heavy alcohol use and normal serum thiamine levels.
  • Clinical observations included impaired consciousness, horizontal nystagmus, and cerebellar ataxia.
  • Diagnosis was made clinically, and high-dose thiamine therapy was administered.
  • Patient demonstrated symptom improvement after the initiation of high-dose thiamine therapy.
  • Initial MRI and CT scans revealed no abnormal findings despite the clinical diagnosis.
  • Normal serum thiamine levels were recorded, emphasizing the need for treatment even in such cases.

Cite This Study

Ono et al. (2023) studied this question.

synapsesocial.com/papers/6a6ec576f44fa9f079dc53b8https://doi.org/10.1136/bcr-2023-254786
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Wernicke encephalopathy2024 · 1 citations
  2. 2Wernicke's Encephalopathy With MRI Findings Despite Coadministration of Thiamine and Glucose2024
  3. 3Wernicke’s encephalopathy associated with alcoholism and precipitated by intravenous glucose2025
  4. 4Non-alcoholic Wernicke's encephalopathy in a thiamine-deficient population: A clinical and diagnostic perspective2025
  5. 5Psychiatric-Predominant Wernicke Encephalopathy With Normal Blood Thiamine Levels: A Case Report2026 · 1 citations