Key result
Arrhythmia-related mortality among older adults in the US increased from 38.0 per 10,000 in 1999 to 47.0 in 2020, with the highest rates observed in men, Non-Hispanic Whites, and the Midwest.
Why the study?
Mortality trends and demographic and geographical disparities in arrhythmia-related deaths among older adults in the United States needed examination.
Observational (n=3,000,000)
Yes
Absolute Event Rate: 47% vs 38%
Arrhythmia-related mortality among older adults in the US has significantly increased from 1999 to 2020, with notable sex, racial, and geographic disparities.
Rising arrhythmia mortality with disparities in older adults warrants targeted awareness; leaves open causal mechanisms and intervention trials.
This study examines mortality trends and disparities in arrhythmia-related deaths among older adults in the United States from 1999 to 2020. Utilizing mortality data from the CDC WONDER database, we analyzed over 3 million arrhythmia-related deaths identified by ICD-10 codes I47.0-I49.9. The study computed age-standardized mortality rates (ASMR) to assess trends across demographic groups and geographical locations. Statistical techniques, including Joinpoint regression analysis, were employed to examine demographic and regional trends in mortality rates. The overall ASMR for arrhythmia-related deaths increased from 38.0 per 10,000 in 1999 to 47.0 in 2020. The trend showed a decline from 1999 to 2009 (APC: −0.9), followed by increases from 2009 to 2018 (APC: 1.5) and a significant rise from 2018 to 2020 (APC: 7.4). Men had higher ASMRs than women (45.2 vs. 33.0), with significant increases observed in both sexes in recent years. Racial disparities were evident, with Non-Hispanic (NH) Whites having the highest ASMR (40.5), followed by NH Blacks (31.1), NH American Indians/Alaska Natives (28.3), Hispanics (22.7), and NH Asians/Pacific Islanders (19.7). Geographic disparities were also prominent, with Vermont exhibiting the highest ASMR (55.8) and Nevada the lowest (24.9). The Midwest region had the highest regional ASMR (41.2), while nonmetropolitan areas consistently showed higher rates than metropolitan areas (42.1 vs. 37.2). These findings highlight significant disparities in arrhythmia-related mortality, underscoring the need for targeted interventions to address these public health challenges. Trends in arrhythmia-related mortality among Older Adults in the United States from 1999 to 2020, with a further illustration of racial and geographical disparities. • Arrhythmia-related deaths in US rose from 38.0 (1999) to 47.0 (2020) per 10,000. • Mortality declined (1999–2009, APC: −0.9), rose (2009–2018, APC: 1.5), spiked (2018–2020, APC: 7.4). • Men accounted for 45.8 % of deaths, with ASMR of 45.2; women had ASMR of 33.0. • NH White population had highest ASMR ( 40.5), followed by NH Black (31.1). • Midwestern and nonmetropolitan regions showed highest ASMRs ( 41.2 and 42.1), urging targeted interventions.
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Cheema et al. (2024) conducted an observational in Arrhythmia-related deaths (n=3,000,000). Time period and demographic/geographic factors was evaluated on Age-standardized mortality rates (ASMR) per 10,000. Arrhythmia-related mortality among older adults in the US increased from 38.0 per 10,000 in 1999 to 47.0 in 2020, with the highest rates observed in men, Non-Hispanic Whites, and the Midwest.
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