Observational study explores serum testosterone's predictive role for hypertension in older males, suggesting important implications for cardiovascular health.
Key Points
The study aims to explore the relationship between serum testosterone levels and hypertension incidence in male patients aged 40 and older.
Analyzed data from 3401 male patients aged ≥40 years over a 4-year period.
Applied linear relationships, generalized additive models, and multivariate regression to the data.
Used receiver operating characteristic curves to evaluate testosterone's predictive role for hypertension.
Hypertensive males aged ≥40 years exhibited significantly lower serum testosterone levels compared to normotensive individuals.
Multivariate regression indicated an inverse association between serum testosterone and hypertension.
ROC analysis showed modest predictive ability of testosterone for hypertension in men aged 40-60, with improved predictability when combined with age, smoking, and BMI for those aged 60-79.