What question did this study set out to answer?

To investigate the associations of serum testosterone and luteinizing hormone with blood pressure and cardiovascular disease risk, and evaluate how hypertension status modifies these relationships in middle-aged and older men.

March 19, 2021Journal of the American Heart AssociationOpen Access

Association of Serum Testosterone and Luteinizing Hormone With Blood Pressure and Risk of Cardiovascular Disease in Middle‐Aged and Elderly Men

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Authors

MQMengyuan QuJiangnan University CFChenzhao FengShihezi University XWXiaotong WangMinistry of Education

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Implication

Cross-sectional study finds inverse hormone links to hypertension in aging men, highlighting complex cardiovascular risks.

Key Points

To investigate the associations of serum testosterone and luteinizing hormone with blood pressure and cardiovascular disease risk, and evaluate how hypertension status modifies these relationships in middle-aged and older men.
Multicenter, population-based cross-sectional study of 5,786 Chinese men (mean age 55.0 ± 10.1 years) sampled across 6 provinces between 2013 and 2016.
Assessed clinical symptoms via questionnaires, measured blood pressure, and evaluated plasma concentrations of total testosterone, free testosterone, luteinizing hormone, and sex hormone-binding globulin.
Hypertension was present in 37.2% (2,150 of 5,786) of men, with total testosterone, free testosterone, and sex hormone-binding globulin showing inverse associations with hypertension prevalence.
In participants with grade 2 hypertension, total testosterone was positively associated with stroke prevalence, and luteinizing hormone was positively correlated with cardiovascular and cerebrovascular diseases.

Cite This Study

Qu et al. (2021) studied this question.

synapsesocial.com/papers/6a75b609117c5bc884dd7ae2 https://doi.org/10.1161/jaha.120.019559

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Association of Serum Testosterone and Luteinizing Hormone With Blood Pressure and Risk of Cardiovascular Disease in Middle‐Aged and Elderly Men

Discussion

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Implication

Key Points

Cite This Study

Association of Serum Testosterone and Luteinizing Hormone With Blood Pressure and Risk of Cardiovascular Disease in Middle‐Aged and Elderly Men

Discussion

Member takes

Implication

Key Points

Cite This Study

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