Key result
A history of preeclampsia in postpartum adolescents was not associated with a higher prevalence of endothelial dysfunction compared to normotensive pregnancies (29.2% vs 21.5%).
Why the study?
Does a history of preeclampsia increase the prevalence of endothelial dysfunction in primiparous adolescents postpartum compared to a normotensive pregnancy?
Cross-Sectional (n=103)
Does a history of preeclampsia increase the prevalence of endothelial dysfunction in primiparous adolescents postpartum compared to a normotensive pregnancy?
Absolute Event Rate: 29.2% vs 21.5%
In primiparous adolescents, a history of preeclampsia is associated with higher postpartum systolic blood pressure but not a significantly higher prevalence of endothelial dysfunction compared to normotensive pregnancies.
No increased endothelial dysfunction found in adolescents with prior preeclampsia; leaves open whether higher postpartum SBP signals future cardiovascular risk.
Objectives: to determine the prevalence of endothelial dysfunction and its association with a history of mild and severe preeclampsia in adolescents. Methods: a cross-sectional study was carried out at the MEAC-UFC with 103 primiparous adolescents postpartum. The assessment of endothelial function was performed by way of flow-mediated dilatation of the brachial artery. Variables (age, body mass index, gestational age at delivery, systolic and diastolic blood pressure and flow-mediated dilation) were compared between groups. p<0.05 was considered to be statistically significant. Results: twenty-four (23.3%) patients had preeclampsia (PE): 11 mild and 13 severe. The overall prevalence of endothelial dysfunction was 23.3% (21.5% of patients with normotensive pregnancies and 29.2% of the PE patients: 18.2% of those with mild PE and 38.5% of those with severe PE). The figures were statistically significant for systolic blood pressure, p=0.007. Conclusions: patients with a history of PE have higher systolic blood pressure than patients with a history of normotensive pregnancy, but did not have more endothelial dysfunction.
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Andrade et al. (2014) conducted a cross-sectional in History of preeclampsia or normotensive pregnancy (n=103). History of preeclampsia vs. History of normotensive pregnancy was evaluated on Prevalence of endothelial dysfunction. A history of preeclampsia in postpartum adolescents was not associated with a higher prevalence of endothelial dysfunction compared to normotensive pregnancies (29.2% vs 21.5%).
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