Key result
Higher mean platelet volume was significantly associated with the presence of microvascular complications in patients with type 2 diabetes mellitus (AOR 1.68; 95% CI 1.37-2.05).
Why the study?
The clinical relevance of platelet indices for assessing the risk of microvascular complications in patients with diabetes mellitus has been largely overlooked.
Are platelet indices associated with microvascular complications in patients with type 2 diabetes mellitus?
Population
352 type 2 DM patients at Debre Berhan Referral Hospital
Comparison
Participants with vs without microvascular complications
Design
Hospital-based cross-sectional study
Authors
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Platelet indices may aid microvascular risk stratification in T2DM; hypothesis-generating and requires prospective validation.
Cross-Sectional (n=352)
No
Are platelet indices associated with microvascular complications in patients with type 2 diabetes mellitus?
Odds Ratio: 1.68 (95% CI 1.37–2.05)
Higher mean platelet volume, platelet distribution width, and platelet-large cell ratio are significantly associated with microvascular complications in patients with type 2 diabetes.
Taderegew et al. (2021) conducted a cross-sectional in Type 2 diabetes mellitus (n=352). Higher platelet indices (MPV, PDW, P-LCR) vs. Lower platelet indices was evaluated on Presence of microvascular complications (AOR 1.68, 95% CI 1.37-2.05). Higher mean platelet volume was significantly associated with the presence of microvascular complications in patients with type 2 diabetes mellitus (AOR 1.68; 95% CI 1.37-2.05).
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