Why the study?
Diabetes mellitus is linked to abnormal platelet function, heightened activation, and vascular complications, prompting evaluation of platelet indices and their relationship with blood sugar levels and complications.
Are platelet indices elevated in individuals with type 2 diabetes compared to healthy controls, and do they correlate with glycemic control and complications?
Population
220 participants (110 diabetics and 110 healthy controls)
Comparison
Diabetics vs healthy controls
Design
Cross-sectional study
Authors
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May support platelet indices as markers of glycemic control and complications in type 2 DM; leaves open clinical utility pending prospective studies.
Are platelet indices elevated in individuals with type 2 diabetes compared to healthy controls, and do they correlate with glycemic control and complications?
Platelet indices such as MPV, PDW, and P-LCR are significantly elevated in type 2 diabetes and correlate with poor glycemic control and vascular complications, suggesting their potential as low-cost prognostic biomarkers.
Patil et al. (2025) studied this question.
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