Key result
ClC-2 and ClC-3 channels are ubiquitously distributed in atrial and ventricular walls, with ClC-3 mRNA levels significantly higher than ClC-2 levels (P<0.05).
Authors
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No immediate clinical implications; leaves open functional roles of cardiac ClC-2/3 channels for further study.
p-value: p=<0.05
Britton et al. (2000) studied this question. ClC-2 and ClC-3 expression was evaluated on Molecular expression and distribution of ClC-2 and ClC-3 in cardiac tissues (p=<0.05). ClC-2 and ClC-3 channels are ubiquitously distributed in atrial and ventricular walls, with ClC-3 mRNA levels significantly higher than ClC-2 levels (P<0.05).
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