Key result
An endogenous digoxin-like immunoreactive substance was detected postoperatively in 16 of 20 adult patients undergoing coronary surgery who were not receiving digoxin treatment.
A digoxin-like immunoreactive substance is detectable postoperatively in a majority of patients undergoing coronary surgery who are not on digoxin therapy.
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May confound digoxin immunoassays after coronary surgery; leaves open clinical relevance and source.
Perioperative digoxin concentrations were measured in 20 unselected adult patients undergoing coronary surgery. None of the patients were receiving treatment with digoxin. A digoxin-like immunoreactive substance was found in 16 patients postoperatively. This substance, if pharmacologically active, may have important clinical implications in the management of patients after open heart surgery.
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NASHEF et al. (1988) studied this question. An endogenous digoxin-like immunoreactive substance was detected postoperatively in 16 of 20 adult patients undergoing coronary surgery who were not receiving digoxin treatment.
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