Key result
Twelve months of abstinence from alcohol in chronic alcoholics significantly improved left ventricular function, including a 16% decrease in the PEP/LVET ratio (P<0.005).
Why the study?
Does 12 months of abstinence from alcohol improve left ventricular function in chronic alcoholics without cardiomyopathy?
Observational (n=24)
Does 12 months of abstinence from alcohol improve left ventricular function in chronic alcoholics without cardiomyopathy?
Effect estimate: -16%
Absolute Event Rate: 0.26% vs 0.31%
p-value: p=<0.005
Abstinence from alcohol for 12 months significantly improves subclinical left ventricular dysfunction and reduces left ventricular mass and wall thickness in chronic alcoholics.
No takes yet. Share an insight, caveat, or question.
May indicate early alcohol-related LV changes in asymptomatic patients; hypothesis-generating for abstinence effects, needing larger studies before clinical adoption.
Milani et al. (2008) conducted an observational in Chronic alcoholism (n=24). Abstinence from alcohol vs. Baseline (before abstinence) was evaluated on PEP/LVET ratio (-16%, p=<0.005). Twelve months of abstinence from alcohol in chronic alcoholics significantly improved left ventricular function, including a 16% decrease in the PEP/LVET ratio (P<0.005).
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