Key result
Chronic alcohol abuse linked to impaired systolic function and a ~12% absolute lower LVEF versus controls.
Why the study?
The exact impact of chronic alcohol abuse on left ventricular systolic function in consecutive subjects without overt heart disease is poorly examined.
Does chronic alcohol abuse impair left ventricular systolic function assessed by 3D ejection fraction and longitudinal strain in adults without overt heart disease?
Observational (n=115)
Does chronic alcohol abuse impair left ventricular systolic function assessed by 3D ejection fraction and longitudinal strain in adults without overt heart disease?
Absolute Event Rate: 48% vs 60%
p-value: p=<0.0001
Chronic alcohol abuse is associated with subclinical left ventricular systolic dysfunction detectable by 3D ejection fraction and longitudinal strain before overt heart remodeling occurs.
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May identify subclinical LV changes in alcohol abuse; leaves open whether novel echo parameters add prognostic value.
Hamala et al. (2019) conducted an observational in Alcohol abuse (n=115). Chronic alcohol abuse vs. Abstinents or drinking ≤8 alcohol units per week was evaluated on Left ventricular ejection fraction (EF) (p=<0.0001). Chronic alcohol abuse was associated with impaired left ventricular systolic function compared to controls, evidenced by reduced ejection fraction (48% vs 60%, P<0.0001).
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