Key result
Preoperative renal dysfunction was associated with increased mortality after non-cardiac surgery, with the risk peaking at an HR of 3.37 (95% CI 2.70-4.22) for eGFR 15.0-29.9.
Why the study?
Does preoperative renal dysfunction increase the risk of postoperative mortality in patients undergoing non-cardiac surgery?
Observational (n=47,245)
Yes
Does preoperative renal dysfunction increase the risk of postoperative mortality in patients undergoing non-cardiac surgery?
Hazard Ratio: 3.37 (95% CI 2.7–4.22)
Preoperative renal dysfunction is a significant risk factor for postoperative mortality after non-cardiac surgery, with risk increasing steeply in patients with moderate to severe kidney dysfunction.
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Preoperative eGFR was associated with postoperative mortality; leaves open whether routine screening improves risk stratification in non-cardiac surgery.
Prowle et al. (2016) conducted an observational in Non-cardiac surgery (n=47,245). Preoperative renal dysfunction (eGFR < 60.0 ml/min/1.73 m2) vs. eGFR ≥ 90.0 ml/min/1.73 m2 was evaluated on Postoperative mortality (HR 3.37, 95% CI 2.70-4.22). Preoperative renal dysfunction was associated with increased mortality after non-cardiac surgery, with the risk peaking at an HR of 3.37 (95% CI 2.70-4.22) for eGFR 15.0-29.9.
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