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March 1, 1995Hypertension

Physiological Determinants of Hyperreactivity to Stress in Borderline Hypertension

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Why the study?

Does borderline hypertension alter hemodynamic and sympathetic nervous system responses to active and passive stress in men?

Population

33 men (12 with borderline hypertension and 21 age-matched normotensive controls), described as white men.

Comparison

Exposure to an active behavioral stressor and a… vs Age-matched normotensive men undergoing the same…

Design

Case-control

Authors

Andrew SherwoodAndrew SherwoodPreventive CardiologyAHAlan L. HinderliterPreventive CardiologyKLKathleen C. LightRutgers, The State University of New Jersey

Discussion

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Implication

Sympathetic hyperreactivity during active stress may mark early hypertension; hypothesis-generating and should not yet change practice.

Structured PICO

Does borderline hypertension alter hemodynamic and sympathetic nervous system responses to active and passive stress in men?

P
Population
33 men (12 with borderline hypertension and 21 age-matched normotensive controls), described as white men.
I
Intervention
Exposure to an active behavioral stressor (aversive reaction time test) and a passive stressor (forehead cold pressor test).
C
Comparator
Age-matched normotensive men undergoing the same stressors.
O
Outcome
Blood pressure changes during stress tests.surrogate

Early stages of hypertension in white men are characterized by sympathetic nervous system hyperreactivity specifically during tasks that elicit active behavioral coping responses.

Cite This Study

Sherwood et al. (1995) studied this question.

synapsesocial.com/papers/6a6f2832f44fa9f079dc904dhttps://doi.org/10.1161/01.hyp.25.3.384

Topics

Hypertension management
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hemodynamic Abnormalities in Borderline Hypertension During Mental Stress1986 · 6 citations
  2. 2Responsiveness to - and -Adrenergic Receptor Agonists Effects of Race in Borderline Hypertensive Compared to Normotensive Men1993 · 62 citations
  3. 3Race, borderline hypertension, and hemodynamic responses to behavioral stress before and after beta-adrenergic blockade.1989 · 73 citations
  4. 4The association of borderline hypertension with target organ changes and higher coronary risk. Tecumseh Blood Pressure study1990 · 258 citations
  5. 5Altered cardiac responsiveness and regulation in the normal cardiac output type of borderline hypertension.1975 · 127 citations