Population
Human coronary arterioles dissected from atrial appendage pieces obtained during cardiac surgery from…
Design
Preclinical
Authors
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Should not change clinical adenosine use; leaves open receptor-specific coronary vasomotor mechanisms for human trials.
Adenosine induces endothelium-independent vasodilation in human coronary arterioles via A2 receptor activation of intermediate-conductance K(Ca) channels, which is opposed by A1 receptor activation.
Sato et al. (2005) studied this question.
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