Key result
Adolescent and adult patients with AD/HD symptoms exhibited a significantly shorter duration of elevated oxygenated hemoglobin in the temporal regions during a verbal fluency task compared to healthy controls.
Why the study?
Does NIRS-measured cerebral blood flow during verbal fluency tasks differ between adults with AD/HD symptoms and healthy controls?
Case-Control (n=10)
No
Does NIRS-measured cerebral blood flow during verbal fluency tasks differ between adults with AD/HD symptoms and healthy controls?
Answers are grounded in this paper and cite their sources.
NIRS reveals shorter durations of elevated oxygenated hemoglobin in adults with AD/HD symptoms during cognitive tasks, suggesting its potential as a biological indicator for executive dysfunction.
Prefrontal dysfunction in patients with attention-deficit/hyperactivity disorder (AD/HD) has been repeatedly detected on a behavioral level, and various brain-imaging studies have elucidated the pathophysiology of AD/HD. Recent advances in near-infrared spectroscopy (NIRS) have enabled noninvasive investigations of brain function in various mental disorders, especially major depression, schizophrenia, and bipolar disorder. The objective of this preliminary study was to use NIRS to evaluate changes in frontal lobe blood flow in post childhood or adult patients with AD/HD symptoms. The subjects included five patients with a range of mental disorders and AD/HD symptoms, and a matched (age, sex, and dominant hand) control group of five healthy subjects. We compared the changes in cerebral blood flow during verbal fluency tasks between the two groups. The duration of the elevated oxygenated hemoglobin was notably shorter in the AD/HD group than that in the healthy control group. We suggest that the shorter elevation durations of oxygenated hemoglobin concentrations might be a biological indicator for post childhood or adult AD/HD or of impaired executive functioning.
No takes yet. Share an insight, caveat, or question.
Matsuo et al. (2014) conducted a case-control in Attention-Deficit/Hyperactivity Disorder (AD/HD) symptoms (n=10). Attention-Deficit/Hyperactivity Disorder (AD/HD) symptoms vs. Healthy controls was evaluated on Changes in oxygenated hemoglobin (oxyHb) concentration during a verbal fluency task (p=<0.05). Adolescent and adult patients with AD/HD symptoms exhibited a significantly shorter duration of elevated oxygenated hemoglobin in the temporal regions during a verbal fluency task compared to healthy controls.
Synapse has enriched 10 related papers. Consider them for comparative context: