Why the study?
Functional near-infrared spectroscopy (fNIRS) may detect differences in prefrontal cortex activation between children with ADHD and typically developing children during inhibitory tasks.
Does functional near-infrared spectroscopy (fNIRS) detect differences in prefrontal cortex activation between children with ADHD and typically developing children during a go/no-go task?
Population
14 children with ADHD and 15 typically developing children
Comparison
Children with ADHD vs typically developing children
Design
Case-control study using fNIRS during go/no-go task
Key result
Children with ADHD exhibited significantly reduced activation in the left frontopolar cortex during a go/no-go task compared to typically developing children.
Authors
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fNIRS may differentiate prefrontal hemodynamics in small ADHD cohorts; leaves open its role as a diagnostic adjunct pending larger trials.
Case-Control (n=29)
No
Does functional near-infrared spectroscopy (fNIRS) detect differences in prefrontal cortex activation between children with ADHD and typically developing children during a go/no-go task?
Absolute Event Rate: 0.023% vs 0.069%
p-value: p=0.008
fNIRS demonstrates reduced left prefrontal cortex activation in children with ADHD during inhibitory tasks, suggesting its potential utility as a diagnostic tool.
Miao et al. (2017) conducted a case-control in Attention-Deficit/Hyperactivity Disorder (ADHD) (n=29). Attention-Deficit/Hyperactivity Disorder (ADHD) vs. Typically developing children was evaluated on Change in oxygenated hemoglobin (oxy-HB) concentration in the left frontopolar cortex (CH48) during go/no-go task (mM·mm) (p=0.008). Children with ADHD exhibited significantly reduced activation in the left frontopolar cortex during a go/no-go task compared to typically developing children.
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