What is the clinical evidence from this study?

Study design: Observational. Population: Mechanical valve thrombosis (n=20). Intervention: Surgical intervention (valve replacement). Primary outcome: Mortality (early and late).

January 1, 2008Journal of Korean Medical ScienceOpen Access

Surgical Management of Mechanical Valve Thrombosis: Twenty-Six Years' Experience

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Key result

Surgical management of mechanical valve thrombosis resulted in a 5% early mortality rate (1 death) and no late mortality over a mean follow-up of 63.3 months.

Population

20 patients who underwent surgical intervention for mechanical valve thrombosis out of 2,298 patients with…

Design

Case_series

Follow-up

mean 63.3+/-49.9 months

Authors

HAHyuk AhnSeoul Veterans Hospital KKKyung Hwan KimHyundai Steel (South Korea)KKKwan Chang KimEwha Womans University

Discussion

Member takes

Implication

May support surgical management in select mechanical valve thrombosis cases; leaves open need for prospective validation in larger cohorts.

Study Design

Type

Observational (n=20)

Multicenter

Structured PICO

Population

20 patients (mean age 42 years, 70% female) who underwent surgical intervention for mechanical valve thrombosis at a single center, followed for a mean of 63.3 months.

Intervention

Surgical management (valve replacement) for mechanical valve thrombosis

Outcome

Surgical outcomes including early mortality, late mortality, and MVT recurrence over follow-uphard clinical

Surgical management of mechanical valve thrombosis is an effective treatment option with low long-term mortality and recurrence rates in this cohort.

Limitations

Retrospective study design.
Small sample size of only 20 patients.
Potential loss to follow-up and inability to rule out unknown sudden death in the broader valve replacement cohort.
The precise role of pannus formation in the pathogenesis of valve thrombosis remains uncertain.
Retrospective design
Small sample size
Potential loss to follow-up (unknown sudden death cannot be ruled out)

Cite This Study

Ahn et al. (2008) conducted an observational in Mechanical valve thrombosis (n=20). Surgical intervention (valve replacement) was evaluated on Mortality (early and late). Surgical management of mechanical valve thrombosis resulted in a 5% early mortality rate (1 death) and no late mortality over a mean follow-up of 63.3 months.

synapsesocial.com/papers/6a6f34cb35aa2c282ce09c62 https://doi.org/10.3346/jkms.2008.23.3.378

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Implication

May support surgical management in select mechanical valve thrombosis cases; leaves open need for prospective validation in larger cohorts.

Surgical Management of Mechanical Valve Thrombosis: Twenty-Six Years' Experience

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Surgical Management of Mechanical Valve Thrombosis: Twenty-Six Years' Experience

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider