Population
Immunoglobulin preparations for intravenous use
Design
Preclinical
Authors
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IVIG titre variability may limit efficacy against enterovirus strains; leaves open whether isolate-specific batch selection improves outcomes in trials.
IVIG preparations show significant intratypic variation in enterovirus antibody titres, suggesting batch selection for specific treatment should be based on the patient's own isolate rather than reference strains.
Galama et al. (1997) studied this question.
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