What question did this study set out to answer?

To evaluate the clinical occurrence, evidence for pathogenicity, and pathogenic mechanisms of the Streptococcus milleri group.

March 1, 1988Clinical Infectious Diseases

Occurrence and Pathogenicity of the Streptococcus milleri Group

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Authors

JGJ GosslingUniversity of Missouri–St. Louis

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Implication

Narrative review reports frequent involvement of Streptococcus milleri in serious suppurative infections and endocarditis, highlighting the need to clarify its true pathogenic mechanisms.

Key Points

To evaluate the clinical occurrence, evidence for pathogenicity, and pathogenic mechanisms of the Streptococcus milleri group.
Synthesized clinical literature on Streptococcus milleri carriage in normal human mucous membranes and clinical disease.
Analyzed bacteriological findings from suppurative and endocardial infections as well as experimental infection models.
The Streptococcus milleri group is routinely isolated from normal human mucous membranes, infective endocarditis cases, and serious suppurative infections occurring more frequently in men.
Evidence linking the group directly to suppurative disease etiology remains largely circumstantial due to frequent co-isolation of other bacterial species and reliance on broad-spectrum therapies.
Experimental induction of non-endocarditis infections in laboratory models has rarely been successful, leaving pathogenic mechanisms largely unestablished.

Cite This Study

J Gossling (1988) studied this question.

synapsesocial.com/papers/6a6f3db175498292b708a2e9 https://doi.org/10.1093/clinids/10.2.257

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Implication

Narrative review reports frequent involvement of Streptococcus milleri in serious suppurative infections and endocarditis, highlighting the need to clarify its true pathogenic mechanisms.

Occurrence and Pathogenicity of the Streptococcus milleri Group

Discussion

Member takes

Implication

Key Points

Cite This Study

Occurrence and Pathogenicity of the Streptococcus milleri Group

Discussion

Member takes

Implication

Key Points

Cite This Study

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