Key result
Male sex was associated with significantly greater intimal medial thickness and a higher prevalence of carotid plaques compared to women, suggesting carotid stenosis is a gender-related trait.
Why the study?
Are there gender-related anatomical and electrophysiologic differences in carotid stenosis?
Population
974 subjects aged 25 to 88 years (478 men and 496 women) with or without carotid stenosis
Design
Cross-sectional
Authors
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Supports sex-stratified carotid research; leaves open whether findings warrant changes to clinical screening or thresholds.
Cross-Sectional (n=974)
Are there gender-related anatomical and electrophysiologic differences in carotid stenosis?
Carotid stenosis exhibits significant gender-related differences, with men demonstrating greater intimal medial thickness and higher plaque prevalence compared to women.
Tromba et al. (2015) conducted a cross-sectional in Carotid stenosis (n=974). Male sex vs. Female sex was evaluated on Anatomical and electrophysiologic differences in the carotid bifurcation (including IMT and plaque prevalence). Male sex was associated with significantly greater intimal medial thickness and a higher prevalence of carotid plaques compared to women, suggesting carotid stenosis is a gender-related trait.