Population
Scallop striated muscle (native and synthetic myosin filaments)
Comparison
Exposure to low ionic strength solutions… vs Physiological ionic strength solutions
Design
Preclinical
Authors
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No immediate clinical implications; leaves open whether scallop subfilament transitions apply to mammalian cardiac thick filaments.
Scallop myosin filaments exhibit a complex substructure of subfilaments and undergo regulatory structural transitions, suggesting accessory proteins contribute to thick filament assembly in vivo.
Vibert et al. (1989) studied this question.
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