Why the study?
Does influenza vaccination alter anticoagulation levels in patients on long-term oral anticoagulant therapy?
Population
145 patients on stable long-term oral anticoagulant therapy, comprising 73 vaccinated patients and 72…
Comparison
Influenza vaccination vs Control group of 72 patients on stable long-term…
Design
Cohort
Follow-up
3 months
Authors
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May indicate reduced warfarin efficacy post-vaccination in elderly; leaves open need for prospective confirmation of INR effects.
Does influenza vaccination alter anticoagulation levels in patients on long-term oral anticoagulant therapy?
Influenza vaccination in elderly patients on long-term oral anticoagulation may reduce warfarin efficacy, necessitating more frequent INR monitoring.
Poli et al. (2002) studied this question.
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