Why the study?
Does the influenza vaccine alter anticoagulation levels (INR) in patients receiving chronic acenocoumarol therapy?
Population
43 patients receiving chronic anticoagulant therapy with acenocoumarol, with stable International Normalized…
Comparison
Trivalent influenza vaccine (91-92 campaign) vs Basal INR values prior to vaccine administration
Design
Cohort
Follow-up
30 days
Authors
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Does not support altering INR monitoring after influenza vaccination; leaves open randomized confirmation in acenocoumarol users.
Does the influenza vaccine alter anticoagulation levels (INR) in patients receiving chronic acenocoumarol therapy?
Administration of the influenza vaccine does not significantly alter INR levels or cause bleeding or thrombotic events in patients on stable chronic acenocoumarol therapy.
Oliver et al. (1993) studied this question.
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