Key result
Cigarette smoking in adult males was associated with significantly higher mean serum levels of C-reactive protein (9.64 vs 1.83 mg/l, p=0.002) and bladder tumor antigen (33.87 vs 26.93 ng/ml, p=0.021) compared to non-smokers.
Why the study?
Does cigarette smoking increase serum levels of C-reactive protein and bladder tumor antigen in healthy adult males?
Population
100 apparently healthy adult males in Nnewi, Nigeria. Excluded individuals with history of inflammatory and…
Comparison
Cigarette smoking vs Non-smoking
Design
Case-control
Authors
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Elevated CRP and BTA levels in smokers may signal inflammation; leaves open any causal link to bladder tumors pending prospective validation.
Case-Control (n=100)
No
Does cigarette smoking increase serum levels of C-reactive protein and bladder tumor antigen in healthy adult males?
Absolute Event Rate: 9.64% vs 1.83%
p-value: p=0.002
Cigarette smoking is associated with significantly elevated levels of C-reactive protein and bladder tumor antigen in adult males, suggesting increased systemic inflammation and potential predisposition to bladder tumors.
PO et al. (2017) conducted a case-control in Healthy (assessing inflammation and bladder tumour risk) (n=100). Cigarette smoking vs. Non-smokers was evaluated on Mean serum C-reactive protein level (mg/l) (p=0.002). Cigarette smoking in adult males was associated with significantly higher mean serum levels of C-reactive protein (9.64 vs 1.83 mg/l, p=0.002) and bladder tumor antigen (33.87 vs 26.93 ng/ml, p=0.021) compared to non-smokers.
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