Key result
Cigarette smoking was associated with significantly higher serum CRP levels compared to nonsmokers (P<0.001), with greater inflammation linked to increased smoking duration and frequency.
Why the study?
Does cigarette smoking increase levels of inflammatory markers in apparently healthy adults?
Population
120 apparently healthy adults in Nnewi metropolis, South East Nigeria
Comparison
Cigarette smoking vs Age-matched nonsmokers
Design
Case-control
Authors
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Highlights a dose-dependent inflammatory response in healthy smokers; reinforces established cardiovascular risk pathways while leaving open the.
Case-Control (n=120)
No
Does cigarette smoking increase levels of inflammatory markers in apparently healthy adults?
p-value: p=<0.001
Cigarette smoking in apparently healthy adults is associated with a significant systemic inflammatory response that is dose- and duration-dependent.
Okocha et al. (2017) conducted a case-control in Healthy adult smokers (n=120). Cigarette smoking vs. Nonsmokers was evaluated on Serum C-reactive protein (CRP) level (p=<0.001). Cigarette smoking was associated with significantly higher serum CRP levels compared to nonsmokers (P<0.001), with greater inflammation linked to increased smoking duration and frequency.
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