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August 5, 2020Frontiers in Public HealthOpen Access

Social support had an indirect negative association with depression (β -0.125) among patients with hypertension, mediated by health literacy and physical comorbidity.

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Why the study?

Depression is common and linked to worse outcomes in hypertension, but the combined effects of social support, physical comorbidity, and health literacy on depression remain unclear.

Population

549 patients with hypertension in rural Sichuan province, China

Design

Cross-sectional survey study

Key result

Social support had an indirect negative association with depression (β -0.125) among patients with hypertension, mediated by health literacy and physical comorbidity.

Authors

BZBaiyang ZhangWZWenjie ZhangXSXiaxia Sun

Discussion

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Member takes

Overview

Mediation pathways in cross-sectional data are hypothesis-generating; prospective studies needed before targeting support or literacy in hypertension.

Study Design

Type

Cross-Sectional (n=549)

Structured PICO

P
Population
549 rural patients with hypertension (mean age 67.7 years, 62.5% female) were surveyed to evaluate the relationships among social support, physical comorbidity, health literacy, and depression.
O
Outcome
Depression (measured by CESD-10 score)patient reported

Main Result

Effect estimate: β -0.125 (95% CI -0.162 to -0.077)

p-value: p=<0.05

In rural patients with hypertension, social support indirectly reduces depression by improving health literacy and reducing physical comorbidities.

Limitations

  • Cross-sectional design does not enable inference of causality.
  • Study was carried out in rural areas of Sichuan Province, limiting generalizability to other regions.

Cite This Study

Zhang et al. (2020) conducted a cross-sectional in Hypertension (n=549). Social support was evaluated on Depression (β -0.125, 95% CI -0.162 to -0.077, p=<0.05). Social support had an indirect negative association with depression (β -0.125) among patients with hypertension, mediated by health literacy and physical comorbidity.

synapsesocial.com/papers/6a6f5c765d37378ac1dc6d5bhttps://doi.org/10.3389/fpubh.2020.00304
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