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March 1, 1989Regional Anesthesia The Journal of Neural Blockade in Obstetrics Surgery & Pain ControlOpen Access

A Comparison of Cardiovascular Responses of Normotensive and Hypertensive Elderly Patients Following Bupivacaine Spinal Anesthesia

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Why the study?

Does pre-existing treated hypertension increase the hypotensive effects of bupivacaine spinal anesthesia in elderly patients?

Population

60 patients aged 75 years or older, divided into 30 normotensive patients and 30 treated hypertensive…

Comparison

Spinal anesthesia performed in lateral decubitus… vs Spinal anesthesia performed in lateral decubitus…

Design

Cohort

Follow-up

60 minutes

Authors

JRJean P. RacleEl Hospital General de Agudos Carlos G. DurandJPJ.Y. PoyEl Hospital General de Agudos Carlos G. DurandJHJean P. HabererCentre Hospitalier Régional et Universitaire de Nancy

Discussion

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Implication

Treated hypertension may heighten hypotension risk during spinal anesthesia in elderly patients; leaves open need for prospective validation before practice change.

Structured PICO

Does pre-existing treated hypertension increase the hypotensive effects of bupivacaine spinal anesthesia in elderly patients?

P
Population
60 patients aged 75 years or older, divided into 30 normotensive patients and 30 treated hypertensive patients.
I
Intervention
Spinal anesthesia performed in lateral decubitus position with 3 ml 0.5% isobaric bupivacaine in treated hypertensive patients.
C
Comparator
Spinal anesthesia performed in lateral decubitus position with 3 ml 0.5% isobaric bupivacaine in normotensive patients.
O
Outcome
Changes from baseline to lowest blood pressures (SBP, MBP, and DBP) during the 60 minutes following intrathecal injection.surrogate

Pre-existing treated hypertension is a significant risk factor for exaggerated hypotensive responses during isobaric bupivacaine spinal anesthesia in elderly patients.

Cite This Study

Racle et al. (1989) studied this question.

synapsesocial.com/papers/6a6f624de71d69abee07fd5ahttps://doi.org/10.1136/rapm-00115550-198914020-00005
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hemodynamic Effects of Spinal Anesthesia in the Elderly1996 · 126 citations
  2. 2Hemodynamic Effects of Spinal Anesthesia in the Elderly1996 · 19 citations
  3. 3Impact of bupivacaine dose on haemodynamics in elderly hip surgery: a randomized controlled trial2026
  4. 4Hemodynamic impact of isobaric levobupivacaine versus hyperbaric bupivacaine for subarachnoid anesthesia in patients aged 65 and older undergoing hip surgery2014 · 19 citations
  5. 5Low dose of isobaric bupivacaine provides lower incidence of spinal hypotension for hip surgery in elderly patients2014 · 4 citations