What does this research mean for the field?

Increased cardiac output following pulmonary vasodilator therapy in group 1 pulmonary hypertension can be mediated by reductions in systemic vascular resistance rather than intrinsic improvements in cardiac function alone. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 1, 2026European Respiratory Journal

High output heart failure in group 1 pulmonary hypertension and clinical outcomes

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Population

Patients with group 1 pulmonary hypertension

Design

Editorial

Authors

AJAjay Kumar JhaJawaharlal Institute of Post Graduate Medical Education and Research

Discussion

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Implication

This letter highlights the need for physiological justifications regarding the mechanism by which pulmonary vasodilator therapy increases cardiac output in pulmonary hypertension.

Structured PICO

Population

Patients with group 1 pulmonary hypertension

Intervention

Pulmonary vasodilator therapy

This letter highlights the need for physiological justifications regarding the mechanism by which pulmonary vasodilator therapy increases cardiac output in pulmonary hypertension.

Cite This Study

Ajay Kumar Jha (2026) studied this question.

synapsesocial.com/papers/6a6f68d4ac440176ef28172b https://doi.org/10.1183/13993003.00509-2026

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Implication

This letter highlights the need for physiological justifications regarding the mechanism by which pulmonary vasodilator therapy increases cardiac output in pulmonary hypertension.

High output heart failure in group 1 pulmonary hypertension and clinical outcomes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

High output heart failure in group 1 pulmonary hypertension and clinical outcomes

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider