Apolipoprotein CIII in Apolipoprotein B Lipoproteins Enhances the Adhesion of Human Monocytic Cells to Endothelial Cells

THP-1 cells (human monocytic cell line), human peripheral blood monocytes, and vascular endothelial cells. Lipoproteins were isolated from fasting plasma of 18 normolipidemic volunteers.

VLDL CIII+, LDL CIII+ (100 microg apoB/mL), or apoCIII itself (100 microg/mL)

VLDL or LDL without apoCIII, apoCI, apoCII, apoE, or HDL CIII+

Adhesion of THP-1 cells or human peripheral blood monocytes to vascular endothelial cellssurrogate