Population
7 unanesthetized, chronically instrumented baboons (Papio anubis and P. cynocephalus)
Comparison
Environmental heating to raise arterial blood… vs Normal state without autonomic blockade during…
Design
Preclinical
Follow-up
1-2 hours per heating session
Authors
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Supports nonautonomic contributions to heat-induced tachycardia; hypothesis-generating and requires human validation before clinical relevance.
In conscious baboons, heat stress-induced tachycardia is mediated by both nonautonomic mechanisms (40%) and autonomic mechanisms (60%, predominantly vagal withdrawal).
Gorman et al. (1984) studied this question.
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