Key result
Nonexertional heat stress in conscious rats increased mean arterial blood pressure from 124 to 151 mmHg (P<0.05), driven by a progressive increase in systemic vascular resistance.
Absolute Event Rate: 151% vs 124%
p-value: p=<0.05
In conscious rats, the pressor response to nonexertional heat stress is driven by systemic vasoconstriction and sympathetic activation rather than increased cardiac output.
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Conscious rat models implicate vasoconstriction in heat stress hypertension; leaves open confirmation in human physiology and clinical settings.
Kregel et al. (1991) studied Nonexertional heat stress (n=33). Nonexertional heat stress vs. Control period at ambient temperature of 24 degrees C was evaluated on Mean arterial blood pressure (p=<0.05). Nonexertional heat stress in conscious rats increased mean arterial blood pressure from 124 to 151 mmHg (P<0.05), driven by a progressive increase in systemic vascular resistance.
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