Role of nitrosyl factors in the hemodynamic adjustments to heat stress in the rat

alpha-chloralose-anesthetized rats (sham-operated and sinoaortic baroreceptor-denervated)

Elevation of core body (colonic) temperature (Tco) from 37 to 39 degrees C, with or without administration of prazosin (100 micrograms/kg i.v.), NG-nitro-L-arginine methyl ester (100 mumol/kg i.v.), or dexamethasone (1 mg/kg i.v.)

Baseline (37 degrees C) and across different pharmacological blockades

Hindlimb vascular resistancesurrogate