Why the study?
Does removal of aortic baroreceptors increase arterial pressure and heart rate in conscious nonhuman primates?
Population
Adult male baboons chronically maintained on a tether system
Comparison
Removal of the aortic baroreceptors vs Baseline (control values prior to deafferentation)
Design
Preclinical
Follow-up
24-h periods
Authors
Loading...
Supports baroreflex control of pressure in primates; leaves open translation to human hypertension therapies.
Does removal of aortic baroreceptors increase arterial pressure and heart rate in conscious nonhuman primates?
Removal of aortic baroreceptors in conscious baboons leads to increased arterial pressure and heart rate, driven by reduced baroreflex sensitivity and increased sympathetic function.
Bishop et al. (1986) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: