Population
Anesthetized dogs instrumented for His bundle and surface electrogram recordings with cannulated…
Comparison
Selective injection of adenosine, dipyridamole… vs Baseline or washout of drugs
Design
Preclinical
Authors
Loading...
Hypothesis-generating for adenosine-mediated ischemic AV block in animals; leaves open clinical translation of antagonists.
Endogenously released adenosine may mediate AV conduction delay and block during ischemia, which can be reversed by adenosine antagonists like aminophylline and theophylline.
Belardinelli et al. (1981) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: