Population
Murine erythroleukaemia cells transfected with the cloned inward rectifier K+ channel IRK1 from mouse…
Comparison
Voltage changes, extracellular K+ concentration… vs Different concentrations of Mg2+, K+, and…
Design
Preclinical
Authors
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Does not alter clinical practice; leaves open whether IRK1 gating modulates cardiac excitability in vivo.
The study characterizes the intrinsic gating mechanisms of the cloned murine IRK1 potassium channel, highlighting its dependence on voltage, extracellular potassium, and intracellular magnesium.
Stanfield et al. (1994) studied this question.
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