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January 1, 2016Sunhwan'giOpen Access

Obese and hypertensive persons were approximately three times more likely to have diastolic dysfunction (OR=2.96, p=0.001) compared to the reference group.

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Why the study?

Does the combination of obesity and hypertension worsen diastolic dysfunction and reduce exercise capacity compared to either condition alone or normal controls?

Population

Subjects with available echocardiographic and treadmill exercise stress test data, categorized as normal…

Comparison

Presence of obesity and hypertension vs Normal controls, obese only, or hypertensive only

Design

Cohort

Authors

JKJinshil KimMKMyeong Gun KimSKSe‐Won Kang

Discussion

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Overview

May flag combined obesity-hypertension for closer monitoring; hypothesis-generating and requires prospective confirmation before practice change.

Structured PICO

Does the combination of obesity and hypertension worsen diastolic dysfunction and reduce exercise capacity compared to either condition alone or normal controls?

P
Population
Subjects with available echocardiographic and treadmill exercise stress test data, categorized as normal control, obese, hypertensive, or obese and hypertensive
I
Intervention
Presence of obesity and hypertension
C
Comparator
Normal controls, obese only, or hypertensive only
O
Outcome
Cardiac function (diastolic dysfunction, echocardiographic parameters) and exercise capacity (exercise time, metabolic equivalents, maximal oxygen uptake)surrogate

The cumulative burden of obesity and hypertension is associated with a significantly increased risk of diastolic dysfunction and reduced exercise capacity.

Cite This Study

Kim et al. (2016) studied this question.

synapsesocial.com/papers/6a6f83aefebe604dd7086be0https://doi.org/10.4070/kcj.2016.46.3.394
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An echocardiographic study of the effect of obesity on systolic and diastolic functions of the left ventricle in hypertensive adults2022 · 1 citations
  2. 2Influence of Mild to Moderate Obesity on Left Ventricular Stress Filling Pattern in Hypertension.1998 · 8 citations
  3. 3Diastolic Stress Echocardiography in Patients With Hypertrophy Cardiomyopathy: Association With Exercise Capacity2024 · 7 citations
  4. 4Exercise capacity affects quality of life and mental stress in hypertensive patients with obesity2025
  5. 5Blood pressure behavior during exercise in patients with diastolic dysfunction and a hypertensive response to exercise2024 · 1 citations