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February 25, 2022Indian Journal of Physiology and PharmacologyOpen Access

An echocardiographic study of the effect of obesity on systolic and diastolic functions of the left ventricle in hypertensive adults

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Key result

Obesity in hypertensive adults was associated with a higher prevalence of left ventricular diastolic dysfunction (78%) compared to non-obese hypertensive adults (58%).

Why the study?

The study was conducted to examine the effect of obesity on echocardiographic parameters of LV systolic and diastolic functions in asymptomatic hypertensive adults.

Does obesity worsen left ventricular systolic and diastolic function in asymptomatic hypertensive adults?

Population

100 asymptomatic hypertensive adults (65 males and 35 females)

Comparison

Obese hypertensives vs non-obese hypertensives

Design

Cross-sectional study

Authors

CSC. Mamatha ShreeKPKulkarni PrashanthBGB Girija

Discussion

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Member takes

Overview

Obesity may impair LV function in asymptomatic hypertensives; hypothesis-generating, prospective studies needed before clinical adoption.

Study Design

Type

Cross-Sectional (n=100)

Multicenter

No

Structured PICO

Does obesity worsen left ventricular systolic and diastolic function in asymptomatic hypertensive adults?

P
Population
100 asymptomatic hypertensive adults aged 40 to 75 years were evaluated cross-sectionally to assess the impact of obesity on left ventricular function.
E
Exposure
Obesity (obese hypertensives)
C
Comparator
Non-obese hypertensives
O
Outcome
Echocardiographic parameters of systolic and diastolic functions of the left ventriclesurrogate

Main Result

Absolute Event Rate: 78% vs 58%

p-value: p=<0.05

Obesity in hypertensive individuals is associated with a significantly higher prevalence of left ventricular diastolic dysfunction compared to non-obese hypertensives.

Cite This Study

Shree et al. (2022) conducted a cross-sectional in Hypertension (n=100). Obesity vs. Non-obese was evaluated on Left ventricular diastolic dysfunction (p=<0.05). Obesity in hypertensive adults was associated with a higher prevalence of left ventricular diastolic dysfunction (78%) compared to non-obese hypertensive adults (58%).

synapsesocial.com/papers/6a99130b7e2600a00478c507https://doi.org/10.25259/ijpp_169_2021
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of Obesity on Left Ventricular Systolic and Diastolic Functions Based on Echocardiographic Indices2023 · 4 citations
  2. 2Evaluation of cardiac performance among asymptomatic obese subjects in comparison with normal individual2019 · 1 citations
  3. 3Effects of isolated obesity on systolic and diastolic left ventricular function2003 · 338 citations
  4. 4Subclinical Regional Left Ventricular Dysfunction in Obese Patients With and Without Hypertension or Hypertrophy2010 · 18 citations
  5. 5Left Ventricular Diastolic Dysfunction and Obesity: A Systematic Review and Meta-analysis of Echocardiographic Studies2016 · 2 citations