Why the study?
Does dietary fish oil supplementation alter the fatty acid composition of human platelet membranes in normal volunteers?
Population
6 normal volunteers
Design
Cohort
Follow-up
4 weeks
Authors
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Selective EPA incorporation into platelet PC/PE without affecting aggregation or TXB2 challenges membrane mobilization as haemostatic mechanism; leaves open alternative pathways.
Does dietary fish oil supplementation alter the fatty acid composition of human platelet membranes in normal volunteers?
EPA incorporation into platelet membrane phospholipids is selective and does not explain the reported beneficial effects of EPA on haemostasis via mobilization from the platelet membrane phospholipid pool.
Galloway et al. (1985) studied this question.
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