Why the study?
Does omega-3 fatty acid supplementation reduce platelet aggregability and thromboxane B2 concentration in healthy mildly overweight men?
Population
44 healthy mildly overweight eastern Finnish men recruited from a representative population sample
Comparison
Omega-3 fatty acids 2.880 g/day for 12 weeks vs Placebo
Design
RCT, double-blind
Follow-up
12 weeks
Authors
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Omega-3 supplementation should not be expected to inhibit platelet function in mildly overweight men; challenges antiplatelet mechanism hypotheses and redirects mechanistic research.
Does omega-3 fatty acid supplementation reduce platelet aggregability and thromboxane B2 concentration in healthy mildly overweight men?
A 12-week supplementation of omega-3 fatty acids does not have a sustained effect on ADP-induced platelet aggregation or thromboxane production in healthy mildly overweight men.
Salonen et al. (1987) studied this question.
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