Amitriptyline can cause reversible QTc prolongation and associated symptoms such as palpitations and dizziness.
Answers are grounded in this paper and cite their sources.
May warrant QTc monitoring on amitriptyline; single case leaves incidence and causality open.
We report a 65-year-old female patient who developed amitriptyline-associated palpitations, dizziness and prolonged QTc interval, four months after therapy had started. The electrocardiogram demonstrated prolonged QTc interval of 505 ms. After cessation of amitriptyline all symptoms reversed and QTc interval normalized to 420 ms.
No takes yet. Share an insight, caveat, or question.
Mandić et al. (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: