The ⁸⁵Sr Scintiscan in Bone Disease

Article1 July 1966The 85Sr Scintiscan in Bone DiseaseGERALD L. DENARDO, M.D.GERALD L. DENARDO, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-1-44 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRoentgenograms of the skeletal system frequently appear normal until late in the clinical course of bone disease (1-4). Bachman and Sproul (5) found roentgenographic changes in only 15 of 31 cases with spinal metastases at postmortem examination despite the antemortem use of tomography. Borak (6) demonstrated that 30 to 50% of the depth of a vertebra had to be lost before the change could be visualized roentgenographically. Abnormalities of the vertebrae, pelvis, sternum, ribs, and scapulae are particularly difficult to detect by conventional roentgenographic techniques. Because of the frequent inability of the routine roentgenogram to demonstrate lesions in the skeletal...References1. MILCHCHANGUS RAGW: Response of bone to tumor invasion. Cancer 9: 340, 1956. CrossrefMedlineGoogle Scholar2. SHACKMANHARRISON RCV: Occult bone metastases. Brit. J. Surg. 35: 385, 1948. CrossrefMedlineGoogle Scholar3. FALCONERLEONARD EHME: Skeletal lesions in Hodgkin's disease. Ann. Intern. Med. 29: 1115, 1948. LinkGoogle Scholar4. PUGH DG: Roentgenologic Diagnosis of Diseases of Bone. The Williams & Wilkins Co., Baltimore, 1951. Google Scholar5. BACHMANSPROUL ALEE: Correlation of radiographic and autopsy findings in suspected metastases in the spine. Bull. N. Y. Acad. Med. 31: 146, 1955. Google Scholar6. BORAK J: Relationship between the clinical and roentgenological findings in bone metastasis. Surg. Gynec. Obstet. 75: 599, 1942. Google Scholar7. 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LAUGHLINMEURKPULLMANSHERMAN JAMLIRA: Bone, skin, and gonadal doses in routine diagnostic procedures. Amer. J. Roentgen. 78: 961, 1957. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Palo Alto, CaliforniaFrom the Nuclear Medicine Service, Veterans Administration Hospital, Stanford School of Medicine, Palo Alto, Calif.Requests for reprints should be addressed to Gerald L. DeNardo, M.D., Chief, Nuclear Medicine Service, Veterans Administration Hospital, Stanford School of Medicine, Palo Alto, Calif. 94304. 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