Why the study?
Is there good agreement among different commercial reagents for measuring PT INR in patients on oral anticoagulation?
Population
150 patients prescribed oral anticoagulation
Comparison
Seven commercial reagents and four calibrator… vs Pairwise comparison among the seven commercial…
Design
Cross-sectional
Authors
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INR method discrepancies may compromise anticoagulation monitoring; leaves open the need for harmonization across commercial assays.
Is there good agreement among different commercial reagents for measuring PT INR in patients on oral anticoagulation?
There is poor agreement among commercial INR methods, which may compromise the monitoring of patients on oral anticoagulation and the application of clinical guidelines.
Horsti et al. (2005) studied this question.
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