Why the study?
Does dietary sodium modification affect blood pressure and plasma atrial natriuretic factor in men with essential hypertension?
Does dietary sodium modification affect blood pressure and plasma atrial natriuretic factor in men with essential hypertension?
In men with essential hypertension, changes in blood pressure in response to dietary sodium are not determined by changes in plasma atrial natriuretic factor.
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Low-sodium diet lowers BP and ANF in essential hypertension; does not support ANF mediation of sodium-BP effects and leaves mechanism open.
McKnight et al. (1994) studied this question.