Population
Caveolin-1 knock out mice and 3T3-L1 adipocytes
Design
Preclinical
Authors
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Caveolin-1 may regulate adipocyte lipid droplet cholesterol in mice; leaves open any role in human cardiometabolic disease.
The study identifies lipid droplets as target organelles for caveolar endocytosis and demonstrates caveolin-1's role in maintaining free cholesterol levels in adipocyte lipid droplets.
Lay et al. (2006) studied this question.
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