Population
In vitro splicing extract of human beta-globin pre-mRNA
Design
Preclinical
Authors
Loading...
Supports hnRNP core proteins as spliceosome components; hypothesis-generating for in vivo roles and therapeutic targeting in splicing disorders.
hnRNP core proteins appear to be present in the complex that performs pre-mRNA splicing and are required for both steps of the splicing pathway.
Sierakowska et al. (1986) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: