What question did this study set out to answer?

Provide practical guidance on laboratory testing for direct oral anticoagulants (DOACs) to avoid diagnostic errors in hemostasis evaluation.

January 1, 2020Arhiv za farmacijuOpen Access

Practical issues in measuring the anticoagulant effect of direct oral anticoagulants

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Why the study?

DOACs influence hemostasis tests and require urgent measurement or monitoring in various clinical situations, necessitating practical guidance to avoid diagnostic errors.

Design

Review

Authors

VDVioleta DopsajUniversity of Belgrade

Discussion

Member takes

Implication

May support transition to DOACs for stroke prevention; leaves open agent-specific long-term outcomes.

Key Points

Provide practical guidance on laboratory testing for direct oral anticoagulants (DOACs) to avoid diagnostic errors in hemostasis evaluation.
Review of clinical indications requiring direct oral anticoagulant quantification, including acute bleeding, emergency interventions, and antidote administration.
Analysis of laboratory interactions between direct factor IIa and factor Xa inhibitors and standard hemostatic assays.
Direct oral anticoagulants interfere with routine coagulation and hemostasis tests, presenting risks of substantial diagnostic misinterpretation.
Twenty-four-hour availability of quantitative DOAC assays in medical centers is essential to direct targeted reversal therapy and acute clinical decision-making.

Cite This Study

Violeta Dopsaj (2020) studied this question.

synapsesocial.com/papers/6a6f9e5af44fa9f079dd150b https://doi.org/10.5937/arhfarm2005297d

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Practical issues in measuring the anticoagulant effect of direct oral anticoagulants

Discussion

Member takes

Implication

Key Points

Cite This Study

Practical issues in measuring the anticoagulant effect of direct oral anticoagulants

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider