Echocardiographic evaluation of Left ventricular function before and after trans-catheter patent ductus arteriosus closure

Introduction: there are limited available studies on LV hemodynamics alteration after trans-catheter PDA closure particularly diastolic function and most of studies are with 2D echocardiography. Objective: to evaluate the effect of trans-catheter closure of PDA on LV systolic and diastolic function in children and young adults using 2D and 3D echocardiography. Materials and methods: Al-Azhar University hospitals hosted this prospective cohort study, which included 20 patients with isolated PDA who had been referred to Cath lab for trans-catheter PDA closure; LV function evaluated by 2D, 3D echocardiography and TDI before, one day after closure and on follow-up. Results: 45% of patients developed post closure LV systolic dysfunction which improved completely after 3 months of follow up, all studied patients showed significant decrease in LAD, LAD/AoD, LVEDd, LVEDs, LVEDVI and LVESVI after 3 months of trans-catheter PDA closure; (LAD/AoD, LVEDVI, LVESVI, FS and LVEF) can be used as predictors of post closure LV systolic dysfunction, diastolic function was worse in individuals with post closure LV systolic dysfunction.